Best AI agent for automation and integrations

Which agents people actually use for automation and integrations, counted from 10 real use cases, with the top examples for each.

Quick answer

Going by documented use cases, not a lab test: of the 10 automation & integrations use cases on agentsetups, Claude appears in 5, Codex appears in 2, Hermes Agent appears in 2.

Most-discussed: Let your different agents talk to each other over Tailscale by Matt Van Horn (Claude, Codex, Hermes Agent, Grok Bot, Meta Muse, Instinct).

Quick start (from Automate D2C support: order tracking, returns, retention by /u/_no__regrets_):

  1. Customer messages on WhatsApp; the agent reads the query.
  2. It checks the database / pulls live order status from Shopify.
  3. Reply with full order details; handle returns and retention flows.

Counts reflect what people post about, not quality or market share.

Last updated · based on 336 use cases on agentsetups, each credited to its author.

Agents by use cases

Agents by number of use cases
AgentUse cases
Claude5
Codex2
Hermes Agent2
Grok Bot1
Meta Muse1
Instinct1
Muse Code1
ChatGPT Dots1

Claude for automation & integrations 5

All 5 Claude automation & integrations use cases →

Codex for automation & integrations 2

Hermes Agent for automation & integrations 2

Grok Bot for automation & integrations 1

Meta Muse for automation & integrations 1

Questions people ask

What is the best AI agent for automation and integrations?

There is no single winner in the data. Of 10 automation & integrations use cases on agentsetups, Claude (5), Codex (2), Hermes Agent (2), Grok Bot (1). Pick the one whose examples look most like your task.

Which AI agents do people use for automation and integrations?

From the sources: Claude (5), Codex (2), Hermes Agent (2), Grok Bot (1), Meta Muse (1), Instinct (1), Muse Code (1), ChatGPT Dots (1).

How do I set up an AI agent for automation and integrations?

Copy a setup that already worked. Automate D2C support: order tracking, returns, retention by /u/_no__regrets_ (n8n): 1) Customer messages on WhatsApp; the agent reads the query. 2) It checks the database / pulls live order status from Shopify. 3) Reply with full order details; handle returns and retention flows. The use-case page has the full prompt.

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